如何研究血小板的功能？一個(gè)重要手段就是體內(nèi)清除血小板，靶點(diǎn)科技攜手德國(guó)Emfret，常備現(xiàn)貨，推出血小板清除抗體，貨號(hào)R300抗體，Antibodies for Mouse Platelet Depletion。如果4 µg抗體/g動(dòng)物體重,可以持續(xù)更長(zhǎng)時(shí)間。注射后60分鐘內(nèi)可以去除血小板95%以上,建議每次注射100-200µL抗體(用無(wú)菌PBS稀釋)。詳情聯(lián)系靶點(diǎn)科技技術(shù)支持。

Specificity: R300抗體，Antibodies for Mouse Platelet Depletion.This antibody preparation contains a mixture of purified rat monoclonal antibodies directed against mouse GPIbα(CD42b). Targeting of this receptor with divalent IgGs results in profound and irreversible Fc-independent platelet depletion in mice. Platelet depletion is frequently used to study the general role of platelets in (patho-) physiology.

清除原理：該抗體制劑含有針對(duì)小鼠 GPIbα（CD42b） 的純化大鼠單克隆抗體的混合物。用二價(jià) IgG 靶向該受體導(dǎo)致小鼠嚴(yán)重且不可逆的 Fc 非依賴(lài)性血小板耗竭。血小板耗竭常用于研究血小板在（病理）生理學(xué)中的一般作用。

血小板的功能：